| — | Xanitos, Inc. | Philadelphia | 1 | 80 | layoff |
| — | WILX Logistics, LLC | Mount Joy | 1 | 70 | closure |
| — | Wilson Creek Energy, LLC | — | 1 | 332 | closure |
| — | White Deer Run Allenwood | Allenwood | 1 | 31 | layoff |
| — | WestRock | Hazelton | 1 | 70 | closure |
| — | Weaber, Inc. | Lebanon, Titusville | 2 | 191 | closure, layoff |
| — | Wawa | Philadelphia | 1 | 0 | closure |
| — | Warwick House, Inc. | Hartsville | 1 | 58 | closure |
| — | Wal-Mart Distribution Center | Bethlehem | 1 | 597 | layoff |
| — | WABTEC Corporation | Wilmerding | 1 | 94 | closure |
| — | VSSI Staffing Services, LLC | York | 1 | 180 | closure |
| — | Vitro Flay Glass, LLC | Carlisle | 1 | 88 | layoff |
| — | Visiting Nurses Association of Greater Philadelphia | Philadelphia | 1 | 114 | closure |
| — | VIMO, Inc. | — | 1 | 430 | layoff |
| — | Vifor Pharma, Inc. | King of Prussia | 1 | 55 | layoff |
| — | VF Corporation | Philadelphia | 1 | 17 | closure |
| — | VF Coporation | Philadelphia | 1 | 12 | closure |
| — | Vestis Services, LLC | Roswell | 1 | 5 | layoff |
| — | University of the Arts | Philadelphia | 1 | 704 | closure |
| — | Universal Protection Service, LLC | Conshohocken | 1 | 72 | layoff |
| — | United States Steel Corporation | Pittsburgh | 1 | 105 | layoff |
| — | United Parcel Service, Inc. (UPS) | New Stanton | 1 | 206 | closure |
| — | United Natural Foods, Inc. (NFI) | Philadelphia | 1 | 48 | closure |
| — | United Natural Foods, Inc. | Harrisburg | 1 | 87 | closure |
| — | Tyson Warehousing Services, LLC | Pottsville | 1 | 314 | layoff |
| — | Tyson Foods | Philadelphia | 1 | 110 | closure |
| — | Trujacodi Delivery Express | Philadelphia | 1 | 42 | closure |
| — | Truestone | Tobyhanna | 1 | 80 | layoff |
| — | True Value | Hanover Township | 1 | 269 | layoff |
| — | Tri-State Envelope | Ashland | 1 | 122 | closure |
| — | Travel + Leisure Resort Development, Inc. | Shawnee-on-Delaware | 1 | 124 | closure |
| — | Transform Warehouse Operations, LLC | Fairless Hills | 1 | 147 | closure |
| — | TransAxle, LLC | Zelienople | 1 | 9 | layoff |
| — | Torrid, LLC | Philadelphia | 1 | 8 | layoff |
| — | Tmunity Therapeutics | Philadelphia | 1 | 14 | closure |
| — | Thomas Jefferson University Hospital | Philadelphia | 1 | 171 | layoff |
| — | The Pep Boys – Manny, Moe & Jack LLC | Philadelphia | 1 | 8 | closure |
| — | The GIANT Company, LLC. | Coopersburg | 1 | 104 | closure |
| — | The Giant Company, LLC | Philadelphia | 1 | 61 | closure |
| — | The Boeing Company | Ridley Park | 1 | 69 | layoff |
| — | The AMES Company | Camp Hill | 1 | 182 | closure |
| — | The AMES Companies | Harrisburg | 1 | 57 | closure |
| — | Technica, LLC | New Cumberland | 1 | 100 | layoff |
| — | TE Connectivity | Waynesboro | 1 | 130 | closure |
| — | Tatano Wire Products, LLC | Lemont Furnace | 1 | 27 | closure |
| — | Taste, Inc. | Philadelphia | 1 | 10 | closure |
| — | Target | Philadelphia | 1 | 47 | closure |
| — | Suburban Community Hospital | Norristown | 1 | 109 | layoff |
| — | Stuffed Puffs, LLC | Bethlehem | 1 | 106 | closure |
| — | Stoelzle Glass USA, Inc. | Monaca | 1 | 200 | layoff |
| — | Stitch Fix, Inc. | Bethlehem | 1 | 393 | closure |
| — | Statewide Automotive | Philadelphia | 1 | 5 | closure |
| — | Starbucks | Philadelphia | 1 | 0 | closure |
| — | SPS Technologies, LLC | Jenkintown | 1 | 251 | layoff |
| — | Spreadshirt, Inc. | Greensburg | 1 | 64 | closure |
| — | Sportsbook | Philadelphia | 1 | 31 | closure |
| — | SpiriTrust Lutheran | Chambersburg | 1 | 0 | closure |
| — | Spark Therapeutics, Inc. | Philadelphia | 1 | 298 | layoff |
| — | Sodexo | Swiftwater | 1 | 83 | closure |
| — | SMBC MANUBANK | — | 1 | 7 | closure |
| — | Silgan Plastics | Langhorne | 1 | 0 | closure |
| — | Shop-Vac USA, LLC | Williamsport | 1 | 80 | layoff |
| — | Sharon Regional Medical Center | Sharon | 2 | 848 | closure |
| — | Schnader, Harrison, Segal & Lewis, LLP | Philadelphia | 1 | 83 | layoff |
| — | Schenker, Inc. | Carlisle | 1 | 478 | closure |
| — | Santander Bank, N.A. | Reading | 1 | 77 | layoff |
| — | Saks, LLC | Wilkes-Barre | 1 | 90 | layoff |
| — | Saks Fifth Avenue | Bala Cynwyd, Wilkes Barre | 2 | 205 | closure |
| — | Saks & Company, LLC | Pottsville | 1 | 435 | closure |
| — | S&S Activewear | Lewisberry | 2 | 346 | closure |
| — | Ryder Integrated Logistics, Inc. | Frackville, Shoemakersville | 2 | 208 | closure |
| — | Rite-Aid | Philadelphia | 1 | 501 | layoff |
| — | Respironics, Inc. | — | 1 | 196 | layoff |
| — | Red Ribbon Bakeshop, Inc. | Philadelphia | 1 | 9 | closure |
| — | RE2, LLC/Sarcos Corp. | Pittsburgh | 1 | 73 | closure |
| — | Radian Group, Inc. | Wayne | 1 | 70 | layoff |
| — | Radial, Inc. | King of Prussia | 1 | 645 | closure |
| — | Quest Diagnostics, Inc. | Norristown | 1 | 121 | closure |
| — | Quality Packaging Specialists International, LLC | Mechanicsburg | 1 | 83 | closure |
| — | Qualfon | Johnstown | 1 | 206 | layoff |
| — | Prysmian Cables and Systems, USA | Schuylkill Haven | 1 | 150 | closure |
| — | PrimeFlight Aviation Services, Inc. | Philadelphia | 1 | 68 | layoff |
| — | PrimeCare Medical, Inc. | York | 1 | 50 | layoff |
| — | PPG Industries, Inc. | Elverson | 1 | 82 | closure |
| — | Pottstown Hospital, LLC. | Pottstown | 1 | 160 | layoff |
| — | Pottstown Hospital | Pottstown | 1 | 131 | layoff |
| — | Post Consumer Brands, LLC | Bloomsburg | 1 | 11 | layoff |
| — | PosiGen Developer, LLC | Conshohocken | 1 | 49 | layoff |
| — | pladis North America, Inc. | Mohnton | 1 | 55 | closure |
| — | Pittsburgh Technical College | Oakdale | 1 | 0 | closure |
| — | Pittsburgh Post-Gazette | Pittsburgh | 1 | 171 | closure |
| — | Pittsburgh Nursing and Rehab Center, PA | Pittsburgh | 1 | 124 | closure |
| — | Pittsburgh Job Corps Center | Pittsburgh | 1 | 180 | closure |
| — | Philips Respironics, Inc. | Mount Pleasant | 1 | 14 | layoff |
| — | PharmaCann, Inc. | Olyphant | 1 | 60 | closure |
| — | Peterson Farms dba Appeeling Fruit Holdings | Dauberville | 1 | 68 | closure |
| — | Peraton, Inc. | Camp Hill | 1 | 153 | layoff |
| — | PepsiCo, Inc. | Harrisburg | 1 | 127 | closure |
| — | Parkhurst Dining, LLC @ the University of the Arts, Philadelphia | Philadelphia | 1 | 34 | closure |
| — | Parkhurst Dining, LLC @ Bucknell University | Lewisburg | 1 | 196 | closure |
| — | Paris Uniform Services | Dubois | 1 | 138 | closure |
| — | Packaging Corporation of America | Allentown | 1 | 60 | closure |
| — | PA Potato Chip Manufacturing LLC | Berlin | 1 | 96 | closure |
| — | Owens and Minor Halyard, Inc. | Mechanicsburg | 1 | 75 | layoff |
| — | Ornua Ingredients, Inc. | Slippery Rock | 1 | 66 | closure |
| — | Offset Paperback Manufacturers, Inc. | Dallas | 1 | 106 | closure |
| — | Oak View Group | Philadelphia | 1 | 0 | layoff |
| — | NRG, Homer City Generating Station | Homer City | 1 | 129 | closure |
| — | NRG Energy, Inc. | New Florence | 1 | 70 | closure |
| — | North Atlantic Ship Repair, LLC | Philadelphia | 1 | 58 | closure |
| — | NFI Interactive Logistics | Bethel | 1 | 124 | closure |
| — | NexTier Completion Solutions, Inc. | Mansfield | 1 | 104 | closure |
| — | NextGen Healthcare, Inc. | Horsham | 1 | 65 | layoff |
| — | Newbold Services, LLC | — | 1 | 294 | layoff |
| — | Natural Foods, Inc. | Schnecksville | 1 | 716 | layoff |
| — | National Fulfillment Services, LLC | Aston | 1 | 45 | closure |
| — | National Distribution Centers, LLC | Newville | 1 | 385 | layoff |
| — | Mulherin’s Pizzeria | Philadelphia | 1 | 39 | closure |
| — | Mountain Valley Golf Course | Barnesville | 1 | 111 | closure |
| — | Motional AD, Inc. | Pittsburgh | 1 | 145 | layoff |
| — | Morrison HealthCare | — | 1 | 478 | layoff |
| — | Morgan Truck Body, LLC | Ephrata | 1 | 92 | closure |
| — | Miller’s Ale House | Philadelphia | 1 | 49 | closure |
| — | Midwest Transport, Inc. | Harmony | 1 | 0 | closure |
| — | Merck & Co., Inc. | North Wales, Riverside | 2 | 168 | closure, layoff |
| — | Megabus Northeast, LLC | Sewickley | 1 | 12 | closure |
| — | Med-Metrix, LLC | Upland | 1 | 142 | closure |
| — | McKesson Corporation | New Castle | 1 | 135 | closure |
| — | Matheson Flight Extenders, Inc. | Sharon Hill | 1 | 75 | closure |
| — | Marsden Services, LLC | Ambridge | 1 | 179 | layoff |
| — | Macy’s Inc. | Philadelphia | 1 | 128 | closure |
| — | LSC Communications – Lancaster WEST Plant | Lancaster | 1 | 380 | closure |
| — | LSC Communications – Lancaster EAST Plant | Lancaster | 1 | 276 | closure |
| — | LNS Chipblaster | Meadville | 1 | 67 | closure |
| — | LivaNova USA, Inc. | Pittsburgh | 1 | 137 | layoff |
| — | Lineage Logistics | East Pottsville | 1 | 208 | layoff |
| — | Lightning Source, LLC | Breinigsville | 1 | 260 | layoff |
| — | Lifescan, Inc. | Malvern | 1 | 0 | layoff |
| — | Liberty Home Choices | Philadelphia | 1 | 615 | closure |
| — | Leviathan Energy, L.P. | Monroeville | 1 | 105 | closure |
| — | Law Practice of Lavin, Cedrone, Graver, Boyd & Disipio | Philadelphia | 1 | 49 | closure |
| — | Kunzler & Company, Inc. | Lancaster | 1 | 193 | closure |
| — | Krise Transportation, Inc. | Milroy | 1 | 0 | layoff |
| — | Knouse Foods Cooperative, Inc. | Chambersburg | 1 | 148 | closure |
| — | Kenco Logistic Services, LLC | Northampton | 1 | 52 | closure |
| — | KeHe Distributors, Inc. | Breinigsville | 1 | 8 | layoff |
| — | Keen Transport, Inc. | Carlisle | 1 | 52 | layoff |
| — | Juvenile Justice Center of Philadelphia | Philadelphia | 1 | 17 | layoff |
| — | Joriki USA, Inc. | Pittston | 1 | 226 | closure |
| — | Johnson & Johnson Consumer, Inc. | Lancaster | 1 | 57 | closure |
| — | Jerith Manufacturing, LLC | Philadelphia | 1 | 61 | closure |
| — | JBS Souderton | Souderton | 1 | 1,485 | closure |
| — | International Vitamin Corporation | Philadelphia | 1 | 203 | closure |
| — | International Paper | Hazelton | 1 | 107 | closure |
| — | Internation Timber and Veneer, L.C. | Jackson Center | 1 | 81 | closure |
| — | Intel Corporation | Allentown | 1 | 56 | layoff |
| — | Instant Web, LLC | Hamburg | 1 | 298 | closure |
| — | Inmar Supply Chain Solutions, LLC | Breinigsville | 1 | 101 | closure |
| — | IG Design Group Americas, Inc. | Berwick | 1 | 380 | closure |
| — | ID Logistics US, Inc. | Scranton | 1 | 108 | layoff |
| — | HVL, LLC | Pittsburgh | 1 | 312 | closure |
| — | Hussian College | Philadelphia | 1 | 23 | closure |
| — | Household Metals, Inc. | Philadelphia | 1 | 71 | closure |
| — | Hood Packaging Corporation | — | 1 | 58 | closure |
| — | HMS Host (located within the Philadelphia International Airport) | Philadelphia | 1 | 13 | layoff |
| — | HMS Host | Philadelphia | 1 | 77 | closure |
| — | Highway Equipment Company, Inc. | Zelienople | 1 | 67 | closure |
| — | Heartland Healthcare Services | Allentown | 1 | 71 | closure |
| — | Hart to Heart Transportation | Philadelphia | 1 | 124 | closure |
| — | Hard Rock Cafe | Pittsburgh | 1 | 55 | closure |
| — | GXO Warehouse Company, Inc. | Mechanicsburg | 1 | 85 | closure |
| — | GXO Logistics Worldwide, LLC | Carlisle | 1 | 69 | layoff |
| — | GXO Logistics Supply Chain, Inc. | Middletown | 1 | 91 | closure |
| — | Guardian Healthcare Management Services | Brockway | 1 | 124 | closure |
| — | Greyhound Lines, Inc. | Philadelphia | 1 | 10 | closure |
| — | Green Leaf Medicals, LLC | Saxton | 1 | 52 | closure |
| — | Grede, LLC | Meadville | 1 | 170 | closure |
| — | Great Dane, LLC | Danville, Elysburg | 2 | 319 | layoff |
| — | GrafTech USA, LLC | St. Marys | 1 | 105 | layoff |
| — | Goodblend Pennsylvania, LLC | Pittsburgh | 1 | 76 | closure |
| — | GIANT Company, LLC | Lancaster, Philadelphia | 2 | 204 | closure |
| — | GEODIS Logistics, LLC | Carlisle, Chambersburg, Kutztown | 3 | 363 | closure, layoff |
| — | Gamestop Fullfillment Center | York | 1 | 155 | closure |
| — | Fulton Bank N.A. | Philadelphia | 1 | 3 | closure |
| — | French Creek Recovery Center | Meadville | 1 | 59 | closure |
| — | Fourth Street Barbecue, Inc. | Charleroi | 1 | 252 | closure |
| — | Forman Mills | — | 1 | 245 | closure |
| — | Forever 21 OpCo, LLC | Philadelphia | 1 | 36 | closure |
| — | FMC Logistics, LLC | Quakertown | 1 | 121 | closure |
| — | First Student Lewisberry | Lewisberry | 1 | 81 | layoff |
| — | First Student | Greensburg, Northampton | 2 | 339 | closure, layoff |
| — | First Quality Retail Services, LLC | King of Prussia | 1 | 18 | layoff |
| — | First Brands Group, LLC, d/b/a Eagle Castings | Hanover | 1 | 73 | closure |
| — | Finance of America Holdings, LLC | Conshohocken | 1 | 43 | layoff |
| — | FedEx Supply Chain, Inc. | York | 2 | 290 | closure, layoff |
| — | Federal Express Corporation | Pittston | 1 | 63 | closure |
| — | Family Dollar Stores of Pennsylvania, LLC | — | 1 | 62 | closure |
| — | Everett Foodliner, Inc. and Saxton Market, Inc. | Everett | 1 | 0 | — |
| — | Ethos Cannabis | Philadelphia | 1 | 11 | closure |
| — | Essendant Management Services, LLC | Phoenixville | 1 | 150 | closure |
| — | ES3 | York | 1 | 69 | layoff |
| — | Eos Energy Storage, LLC | East Pittsburgh | 1 | 251 | layoff |
| — | Envision Physician Services | Conshohocken | 1 | 162 | layoff |
| — | Engineered Materials Solutions | Hamburg | 1 | 58 | closure |
| — | Eagle Sight Delivery, LLC | Huntingdon Valley | 1 | 55 | closure |
| — | Durham School Services | Philadelphia | 1 | 299 | layoff |
| — | DuBois Logistics, LLC | DuBois | 1 | 110 | closure |
| — | Donna Bella Farms, LLC | Temple | 1 | 161 | layoff |
| — | Dometic | Limerick | 1 | 89 | closure |
| — | DHL Supply Chain | Bethlehem, Elizabethtown | 2 | 334 | closure |
| — | Devon Seafood Grill | Philadelphia | 1 | 76 | closure |
| — | Del Frisco’s Grille | Philadelphia | 1 | 51 | closure |
| — | David’s Bridal, LLC | — | 1 | 9,236 | layoff |
| — | DAS Companies, Inc. | Palmyra | 1 | 100 | layoff |
| — | Dan Schantz Farm & Greenhouses, LLC (UPDATED) | Allentown | 1 | 120 | closure |
| — | D&A Consulting Service, LLC | — | 1 | 14 | layoff |
| — | Cygnus Home Service, LLC d/b/a Yelloh | — | 1 | 86 | layoff |
| — | Cygnus Home Service, LLC | — | 1 | 55 | layoff |
| — | CVS Health | Blue Bell | 1 | 157 | layoff |
| — | Customized Distribution Services, Inc. | Breinigsville | 1 | 107 | closure |
| — | Custom Glass Solutions | Trumbauersville | 1 | 105 | closure |
| — | CSL Behring, LLC | Philadelphia | 1 | 3 | closure |
| — | Crozer Health | — | 1 | 2,651 | closure |
| — | Crothall Healthcare @ Wellspan Health | York | 1 | 64 | layoff |
| — | Crothall and Morrison Healthcare | Philadelphia | 1 | 795 | layoff |
| — | Corelle Brands, LLC | Charleroi, Greencastle | 2 | 593 | closure |
| — | Conduent Commercial Solutions, LLC. | Florham Park | 1 | 9 | layoff |
| — | Comprehensive Logistics, Inc. | York | 1 | 365 | layoff |
| — | Compass Group USA, Inc. | Philadelphia | 1 | 110 | closure |
| — | Coca Cola | Allentown | 1 | 58 | layoff |
| — | Cleveland-Cliffs, Inc. | Steelton | 1 | 559 | layoff |
| — | Cleveland Cliffs Plate, LLC | Conshohocken | 1 | 107 | layoff |
| — | CJB Logistics | Philadelphia | 1 | 101 | closure |
| — | CJ Logistics America, LLC | Breinigsville, Newville | 2 | 113 | closure |
| — | Citizens Bank | Philadelphia | 1 | 0 | closure |
| — | Church World Service (CWS), Inc. | Lancaster | 1 | 65 | layoff |
| — | Church & Dwight Company, Inc. | York | 1 | 195 | layoff |
| — | Chick-fil-A | Philadelphia | 1 | 49 | closure |
| — | Chewy, Inc. | Mechanicsburg | 1 | 522 | closure |
| — | Chartwells | York | 1 | 6 | layoff |
| — | Chart House | Philadelphia | 1 | 36 | closure |
| — | Chandler Hall Health Services | Newtown | 1 | 220 | closure |
| — | Century Therapeutics, LLC | Philadelphia | 1 | 72 | layoff |
| — | Central Admixture Pharmacy Services, Inc. | Allentown | 1 | 173 | closure |
| — | Carson Valley Children’s Aid | Norristown | 1 | 96 | closure |
| — | Caring People Alliance | — | 1 | 123 | closure |
| — | Cargill Cocoa & Chocolate, Inc. | Hazle Township | 1 | 102 | closure |
| — | Calfrac Well Services Corp. | Smithfield | 1 | 75 | closure |
| — | Cabrini University | Radnor | 1 | 363 | closure |
| — | Cabinetworks, LLC | Thompsontown | 1 | 420 | closure |
| — | C.H. Briggs | Reading | 1 | 104 | closure |
| — | BVPV Styrenics, LLC | Monaca | 1 | 140 | layoff |
| — | Bush Industries, Inc. | Erie | 1 | 51 | closure |
| — | Burch Logistics, LLC | Philadelphia | 1 | 54 | closure |
| — | Brook & Whittle | Croydon | 1 | 72 | closure |
| — | Brinks Home | Dallas | 1 | 81 | layoff |
| — | Bradford Regional Medical Center | Bradford | 1 | 238 | closure |
| — | BPM Limited | Chesterbrook | 2 | 148 | layoff |
| — | Bowhead Logistics Management, LLC (Letterkenny Army Depot) | Chambersburg | 1 | 61 | layoff |
| — | Bowhead Logistics Management, LLC | Chambersburg | 1 | 307 | layoff |
| — | Bowery Farming, Inc. | Bethlehem | 1 | 104 | layoff |
| — | Bonnie Plants, LLC | Blairsville | 1 | 65 | closure |
| — | Bon Appetit Management Company @ Grove City College | Grove City | 1 | 185 | closure |
| — | Bon Appetit Management Company | Easton | 1 | 194 | closure |
| — | Boeing Company | Smithfield | 1 | 101 | layoff |
| — | BLST Operating Company, LLC | Warren | 1 | 23 | layoff |
| — | Block, Inc. | — | 1 | 22 | layoff |
| — | BIOLYST Scientific | Hatfield | 1 | 76 | closure |
| — | Big Lots, Inc. | Tremont | 1 | 505 | layoff |
| — | BH Security, LLC (d/b/a Brinks Home) | — | 1 | 42 | layoff |
| — | Berkley Medical Resources, Inc. | Smithfield | 1 | 0 | closure |
| — | Bergen Logistics | Wilkes-Barre | 1 | 100 | closure |
| — | Benefits Data Trust | Philadelphia | 1 | 273 | layoff |
| — | Bedding Acquisition, LLC | Pottsville | 1 | 112 | closure |
| — | Bakery Barn, LLC | Pittsburgh | 1 | 82 | closure |
| — | AVI Foodsystems, Inc. | Philadelphia | 1 | 297 | closure |
| — | Assurant | York | 1 | 442 | closure |
| — | Ascent Tubular Products | Munhall | 1 | 114 | layoff |
| — | Arway Uniform and Linen Rentals | Philadelphia | 1 | 85 | closure |
| — | Aramark Campus, LLC | Meadville | 1 | 94 | layoff |
| — | American Medical Response Mid-Atlantic, Inc. | Philadelphia | 1 | 152 | layoff |
| — | American Expediting Logistics, LLC | Media | 1 | 86 | closure |
| — | Amazon Fresh | — | 1 | 0 | layoff |
| — | Amazon | Imperial | 1 | 432 | layoff |
| — | Alpha & Omega Logistics Corporation | Ambler | 1 | 110 | closure |
| — | ALPEK Polyester USA, LLC | Reading | 1 | 100 | closure |
| — | Alloy Surfaces Company, Inc. | Chester Township | 1 | 52 | closure |
| — | Allen Distribution | Allentown | 1 | 70 | closure |
| — | Air Products and Chemicals, Inc. | Allentown | 1 | 14 | layoff |
| — | Affirm, Inc. | Pittsburgh | 1 | 60 | layoff |
| — | Advantest, Inc. | Allentown | 1 | 55 | layoff |
| — | Adare Pharmaceuticals, Inc. | Philadelphia | 1 | 137 | closure |
| — | ACC Premiere | Montoursville | 1 | 67 | layoff |
| — | ABA2DAY Behavior Services | Newtown Square | 1 | 94 | closure |